Lenzetto is considered safe and effective for many women when prescribed appropriately, and its transdermal delivery offers a favourable risk profile compared to oral HRT. As with all HRT, the benefits and risks are highly individual and depend on your personal medical history. It may not be suitable for women with a history of certain conditions, including oestrogen-dependent cancers or undiagnosed genital bleeding. As with any medication, it is important to have a conversation with a healthcare professional to assess whether it is the right option based on your individual circumstances.

Lenzetto is suitable for perimenopausal and postmenopausal women looking for a discreet, easy-to-use alternative to patches, gels, or tablets. The spray method delivers hormones transdermally, meaning they enter your bloodstream without passing through your digestive system first, which can be beneficial for women who experience digestive issues with oral HRT. If you still have your womb, your clinician will prescribe a progestogen alongside Lenzetto to protect the womb lining. There are certain medical conditions that mean Lenzetto may not be suitable for you, and your clinician will review these before prescribing.

The estradiol in Lenzetto is chemically and biologically identical to the oestrogen naturally produced by your ovaries. It is derived from plant-based starting materials and undergoes processing to produce a molecule your body recognises and processes exactly as it would its own naturally produced oestrogen. This is why it is referred to as "body identical," and it is considered a well-tolerated and effective option for many women using HRT.

Lenzetto is one of several HRT options available through Voy. During your consultation, your prescriber will review your symptoms, medical history, and treatment goals to recommend the most suitable option. Whilst many women use Lenzetto successfully, your individual circumstances determine whether it is the best choice for you.

Some women may also notice fluid retention, leg cramps, changes in libido, mild abdominal discomfort, or vaginal spotting. Vaginal spotting is more likely if you have a womb and are not taking sufficient progestogen alongside Lenzetto.

Most women experience some adjustment symptoms during the first few weeks as the body adapts to new hormone levels. These effects typically diminish within the first month and should largely resolve by your three-month review, which is considered the standard adjustment period. If side effects persist, a dose adjustment or alternative formulation may help.

Contact your clinician if side effects are significantly affecting your daily life, persist beyond three months without improvement, or if skin irritation becomes severe or does not improve when you change application sites. If you are not getting on well with Lenzetto, alternative transdermal options such as a gel or patch, or oral oestrogen, may be considered. Severe allergic reactions are rare but require immediate medical attention. Seek emergency care if you experience sudden facial or throat swelling, difficulty breathing, or rapidly developing hives.