Wegovy 0.5mg

Inject Wegovy once a week into the stomach, thigh or upper arm.

See our step-by-step Wegovy injection guide.

There is no exact equivalence. Wegovy (semaglutide) and Mounjaro (tirzepatide) contain different active ingredients and work differently, so doses are not directly interchangeable.

At Voy, we review your treatment history (current dose, progress, side effects, goals) to recommend a safe switch and the most appropriate starting dose for you. Our switch guidance uses the best available evidence, expert input and real-world outcomes to balance effectiveness with safety.

0.5mg is the second step in the treatment plan, but it is still an early stage. Some people notice appetite changes at this dose, while many need to increase further to see steady weight loss. Stay consistent with weekly dosing and support treatment with diet, activity and sleep. If side effects are mild and weight is not moving, speak to your clinician about increasing the dose.

It is stronger than 0.25mg, and for some people it provides good control of appetite and weight. Many will continue to increase the dose to find the level that works best for them.

The active ingredient in Wegovy, semaglutide, has a half-life of around 7 days, meaning about half the medicine is cleared from your body each week. After 3 to 4 weeks, more than 90% has left the body, with only small traces remaining by around 5 weeks.

Yes. Some people experience good appetite suppression and early weight loss at 0.5mg, while for others it is still a low, adjustment dose. Many need to increase the dose further to see steady weight loss. Read our week-by-week Wegovy guide.

Yes. 0.5mg is a stronger dose than 0.25mg, so it helps your body adjust further and can reduce appetite more noticeably. Some people start to see weight loss at this stage. For more visible results, most need to increase gradually to higher doses as part of their titration schedule. You can also support your progress through diet, exercise and good sleep.

Each Wegovy 0.25mg dose is 0.37 mL of solution, but you don’t need to measure it yourself. The FlexTouch pen is preset, so you simply twist to 0.25mg to load one dose and inject. Each pen contains four doses.

0.25mg is the starter dose to help your body adjust. 0.5mg is the next step, often with stronger appetite suppression and potential for more weight loss.

Through regulated private providers like Voy or, in some cases, through NHS specialist weight-management services. NHS eligibility is stricter and usually requires health problems related to weight and a higher BMI (often 35 or above). Lower BMI criteria may apply for some ethnic groups.