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Home/Guides & Tips/Medications/

Wegovy dosage

Wegovy dosage guide for weight loss: Everything you need to know

Starting Wegovy? This detailed guide walks you through the dosage schedule, explaining why gradual increases matter and what to do if you miss a dose.

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Medically reviewed by

Dr Earim Chaudry (MBBS), Chief Medical Officer

iconUpdated 12th June, 2025
Research-Based Guide
Table of contents
  • Wegovy doses
  • Wegovy dosing schedule
  • Wegovy dosage chart
  • Wegovy starting dose
  • Wegovy maintenance dose
  • Wegovy maximum dosage
  • How many doses are in a Wegovy...
  • At what dose does Wegovy start...
  • What happens if I miss a dose ...
  • How to inject Wegovy?
  • Are there any Wegovy side effe...
  • Getting started on Wegovy

Wegovy is a weight loss treatment that’s making waves for a reason. Its active ingredient is semaglutide, which mimics the naturally-occurring GLP1 hormone, making you feel fuller for longer and helping to manage cravings.

Medicines such as Wegovy or Mounjaro are in high demand because they work for lots of people: one study showed those using semaglutide lost 15% of their body weight on average, whereas individuals who just made lifestyle changes lost around 2.5%.

When you first start taking Wegovy weight loss injections, your clinician will set you up on a dosage schedule with a low starting dose to ensure safety, effectiveness and long-term results. Here, we’ll take you through the Wegovy dose schedule step by step.

Wegovy doses

The Wegovy dosage schedule is designed for the best weight loss results and for your safety. You inject a dose of Wegovy once a week, on the same day every week, using a prefilled pen.

The schedule always starts with the same low starting dose—0.25mg per week for four weeks. Then, your dose will automatically increase every four weeks until your clinician finds the right dose for you. If you experience issues with a particular dose, you can contact your clinician to review your plan.

Why do I need a dosage schedule?

You might be wondering: “why can’t I just jump to the full dose if that’s what works?” It’s a fair question! But think of it like training for a marathon. You wouldn’t start by running 26 miles on your first day, right? You’d build up to it gradually.

The same goes for Wegovy. Starting with a lower dose gives your body time to adjust, helping to minimise side effects and ensure the treatment works for you in the long run. This step-by-step approach is key to achieving safe, sustainable weight loss.

What are the Wegovy injection doses for weight loss?

There are five Wegovy doses for weight loss that a clinician might prescribe: Wegovy 0.25mg, Wegovy 0.5mg, Wegovy 1mg, Wegovy 1.7mg, Wegovy 2.4mg.

Wegovy dosing schedule

It’s important to follow the recommended titration plan, which gradually increases your dose every four weeks (or when your clinician recommends moving you up).

Some people may need more time at a lower dose before moving up to the next step. Always check with your healthcare provider before making any changes to your schedule.

If you ever need to pause or slow down, your healthcare provider can help you adapt the schedule to suit your needs—what matters most is finding a pace that works for you.

Here’s what the Wegovy dosage schedule might look like as your treatment progresses:

  • Week 1 to 4: 0.25mg (per week)
  • Week 5 to 8: 0.5mg (per week)
  • Week 9 to 12: 1.0mg (per week)
  • Week 13 to 16: 1.7mg (per week)
  • From week 17: 2.4mg (per week)

Wegovy dosage chart

Wegovy doses chart

Wegovy starting dose

Everyone starts Wegovy on 0.25mg per week for four weeks. After this, doses are usually increased bit by bit every four weeks unless you experience side effects or want to remain on the dose you’re on.

Wegovy maintenance dose

The maintenance dose is the maximum recommended Wegovy dose, meaning you won’t need to increase your dose beyond this. For most people, the maintenance dose is 2.4mg. After week 17, you continue with the maintenance dose once a week as per your treatment plan. Some Wegovy users stay on a lower dose as their maintenance dose. It’s all about what your doctor recommends!

While it might feel tempting to skip ahead to the maintenance dose, it’s best to follow your clinician’s guidance. The gradual increase helps your body adjust and leads to more effective, long-lasting results. Plus, your clinician will monitor your progress and tailor your treatment to what works best for you.

Wegovy maximum dosage

The maximum recommended dose of Wegovy is 2.4mg of semaglutide every week. This is the dose that’s shown to deliver the most significant weight loss benefits in clinical trials. But as we’ve explained, you don’t start taking 2.4mg of Wegovy straightaway. You build up to it gradually to minimise the risk of side effects, and for your body to get used to the medication.

At the 2.4mg maintenance dose, most people experience the full appetite-suppressing effects of semaglutide, which can make it easier to reach your health goals.

What if you can’t tolerate the maximum dose?

Not everyone can or needs to reach the 2.4 mg dose. Some people find they respond well to a lower dose, such as 1.7mg, and may stay on that long-term. If side effects are a barrier, your healthcare provider may recommend sticking with a lower dose that your body can tolerate.

The key is finding the right balance between effectiveness and comfort. Lower doses can still lead to meaningful weight loss, especially when supported by healthy habits.

How many doses are in a Wegovy pen?

There are four doses in each Wegovy pen. As Wegovy is injected weekly, one pen will last four weeks.

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At what dose does Wegovy start working?

Everybody is different, and some people may start to lose weight on lower doses, for others this may happen at higher doses. Your metabolism, lifestyle and how closely you stick to the dosage schedule can influence the amount and rate of weight loss. This is totally normal.

Wegovy is recommended alongside a healthy, balanced diet and physical activity, so you are more likely to reach your goals by eating fruit and vegetables, wholegrain and lean protein. And try to fit in 150 minutes of moderate exercise a week—activities like walking, jogging, or even dancing count! At Voy, our dedicated and compassionate coaches will help you find the lifestyle changes that work best for you.

What happens if I miss a dose of Wegovy?

Life happens, and it’s okay if you forget a dose. Here’s what to do:

If you forget to take Wegovy on your scheduled day, take it as soon as possible within five days after the missed dose.

If more than five days have passed, skip the missed dose and administer the next dose on your regularly scheduled day.

If you forget to take three or more doses of Wegovy, contact your clinician to review your treatment plan.

Whatever you do, don’t take a double dose to make up for it. If you accidentally take multiple doses in a week, contact your doctor right away. Missing a dose won’t ruin your progress—just get back on schedule as soon as possible.

How to inject Wegovy?

Wegovy is injected using a prefilled pen, which is provided to you. Using a Wegovy pen is straightforward. The injection is subcutaneous, meaning you inject it into the fatty tissue just under your skin—common areas include your upper arms, upper legs, or stomach. Avoid injecting into veins, muscles, or scarred areas. Take a look at our handy video that guides you through the process of injecting Wegovy.

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Are there any Wegovy side effects to look out for?

Like starting any new medicine, you may experience some mild side effects after your first dose of Wegovy while your body gets used to it. These could include nausea, vomiting, diarrhea or fatigue, but research suggests they tend to be mild and ease as your body adapts to the Wegovy doses. Some people notice a bit of discomfort at the injection site too.

There are things you can do that could reduce the risk of side effects when starting Wegovy. Staying hydrated is important, as water helps our bodies to absorb medication more effectively. Because Wegovy slows digestion, eating smaller meals can also help. Like with any sickness, getting some fresh air and avoiding very rich or spicy food can sometimes ease symptoms too. It’s a good idea to limit your alcohol intake too.

Side effects support at Voy

"If you're using Voy and you experience any side effects, rest assured that our expert clinicians are just a message or phone call away. They can adjust your dose, prescribe medication to ease your symptoms, or simply offer reassurance.

Everyone responds differently to weight loss treatment and we'll help you find what feels right for you."

Phoebe Fox - Weight Loss Specialist Clinician

Getting started on Wegovy

Like starting any new medicine, you may experience some mild side effects after your first dose of Wegovy while your body gets used to it. These could include nausea, vomiting, diarrhea or fatigue, but research suggests they tend to be mild and ease as your body adapts to the Wegovy doses. Some people notice a bit of discomfort at the injection site too.

There are things you can do that could reduce the risk of side effects when starting Wegovy. Staying hydrated is important, as water helps our bodies to absorb medication more effectively. Because Wegovy slows digestion, eating smaller meals can also help. Like with any sickness, getting some fresh air and avoiding very rich or spicy food can sometimes ease symptoms too. It’s a good idea to limit your alcohol intake too.

FAQ

Wegovy dosage: FAQ

Dr Earim Chaudry, MBBS
DisclaimerAt Voy, we ensure that everything you read in our blog is medically reviewed and approved. However, the information provided is not meant to replace professional medical advice, diagnosis, or treatment. It should not be relied upon for specific medical advice.
References
icon¹

Moiz, Areesha et al., “Long-Term Efficacy and Safety of Once-Weekly Semaglutide for Weight Loss in Patients Without Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials”, The American Journal of Cardiologyscribble-underline, Volume 222, 2024, 112-130. pubmed.ncbi.nlm.nih.gov/38679221/

icon²

‘Semaglutide for Managing Overweight And Obesity’, scribble-underlineNational Institute for Health and Care Excellence.www.nice.org.uk/guidance/ta875, 8 Mar. 2023

icon³

“Wegovy: Package Leaflet, Information for the Patient.” Electronic Medicines Compendium. www.medicines.org.uk/emc/files/pil.13800.pdf. Accessed 9 Dec 2024.

icon⁴

Wilding, John T.H et al., ‘Once-Weekly Semaglutide in Adults with Overweight or Obesity’, The New England Journal of Medicine, VOL. 384 NO. 11, February 10 2021. scribble-underlinehttps://www.nejm.org/doi/full/10.1056/NEJMoa2032183

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