Evorel Sequi

Evorel Sequi is intended for women who are perimenopausal or in early postmenopause and still have their womb. It's particularly suitable for those experiencing irregular periods and seeking a treatment that mimics the natural menstrual cycle.

Sequential HRT involves taking oestrogen continuously and adding progestogen for part of the cycle, leading to regular withdrawal bleeding. This approach is often recommended for women who are still menstruating or have recently stopped.

Typically, a withdrawal bleed occurs during the fourth week of the cycle, when using the combined patches.

One Evorel 50 patch is applied twice weekly for two weeks, followed by one Evorel Conti patch applied twice weekly for the next two weeks. Patches should be changed on the same days each week.

• Evorel Sequi is sequential and leads to monthly bleeding. It’s for people who are still having periods.
• Evorel Conti is continuous combined HRT with no regular bleeding, and is used after periods have stopped.

Yes, a withdrawal bleed typically occurs during the fourth week of the cycle, mimicking a natural period.

There’s no strong evidence that HRT causes weight gain. Some people experience fluid retention or body composition changes during menopause, but lifestyle factors such as diet, sleep, and exercise usually have a greater impact on weight.