They’re both weight loss injections that work by making you feel full. But retatrutide and Wegovy are quite different.
So, what sets them apart? Read on to find out.
Is retatrutide better than Wegovy?
First, a caveat: retatrutide isn’t approved yet, so a clinician can’t prescribe it to you.
However, based on the data we have so far, retatrutide appears to be very effective for weight loss. After 48 weeks, the average loss on retatrutide is 24.2% body weight.
Whereas, a 7.2mg dose of Wegovy led to an average loss of 20.7% after 72 weeks.
By the way: these results are from separate clinical trials, so we can’t really compare them directly. However, they can give us a sense of how well each medicine works.
Weight loss is a personal journey and there’s no single “best” medicine for it. There’s only what works for you. At Voy, our clinicians will work with you to create the perfect plan—whether that includes Wegovy weight loss injections or another medicine.
Retatrutide vs Wegovy
Let’s take a closer look at how these two compare.
How is retatrutide different from Wegovy (semaglutide)?
The main thing that sets retatrutide and Wegovy apart is how they work.
Both mimic the effects of your body’s natural hormones to slow your digestion and keep cravings at bay.
But Wegovy only acts like one hormone, GLP-1. Whereas retatrutide mimics three: GLP-1, GIP, and GCG.
This triple action is why retatrutide is so potent.
You can also compare it with Ozempic in our guide: Retatrutide vs Ozempic.
How fast can you lose weight on retatrutide and Wegovy?
Everyone’s different, so we can’t say for sure how fast you’ll see results. But people on either medicine might notice their appetite start to curb within the first few weeks.
Wegovy vs retatrutide: side effects
Common symptoms are similar for both retatrutide and Wegovy:
- Nausea
- Diarrhoea
- Vomiting
- Constipation
This list isn’t exhaustive. Check in with your provider if you’re worried about side effects.
Side effects support at Voy
"If you're using Voy and you experience any side effects, rest assured that our expert clinicians are just a message or phone call away. They can adjust your dose, prescribe medication to ease your symptoms, or simply offer reassurance.
Everyone responds differently to weight loss treatment and we'll help you find what feels right for you."

Wegovy vs retatrutide: cost
We don’t know how much retatrutide will cost until it launches. But it will probably be priced similarly to Wegovy and Mounjaro weight loss injections. Prices can vary between private providers.
Whatever you do, make sure you’re buying from a registered provider. Otherwise, there’s no guarantee the products are genuine or safe to take.
How can you get Wegovy and retatrutide in the UK?
As a refresher: retatrutide isn’t available in the UK because it isn’t approved yet.
Wegovy is available on the NHS. But for now it’s limited to people who meet strict criteria and whose GP is part of the rollout.
If you don’t meet NHS criteria or want to explore treatment sooner, you may already be eligible through a private prescription—including through our weight loss programme. We’ll post you monthly weight loss medication and help you to transform your lifestyle, so you keep the weight off for good.
By the way: as well as Wegovy and other approved weight loss injections, we’ve got orlistat weight loss capsules, too.
Our Voy weight loss results speak for themselves: 94% say it’s the best weight loss programme they’ve tried. Take our quiz to see if you’re eligible.








