Mounjaro 2.5mg

The 2.5mg dose is the standard starting point for everyone, regardless of weight or health status. This lower dose helps minimise side effects while your body adjusts. Your clinician will assess your tolerance before recommending dose increases. If you’re feeling a good level of appetite suppression on this dose, and seeing weight loss, there’s no requirement to increase the dose.

Mounjaro 2.5mg is primarily a starting dose to help your body adjust to the medication. For weight loss, research shows an average of 4% body weight reduction during the first month. For diabetes, it begins improving blood glucose control, though full benefits typically emerge at higher doses.

Most people notice some changes in appetite within the first few weeks, however it can take up to 8 weeks to start seeing the effects. Visible weight loss typically begins after 2-3 weeks on Mounjaro 2.5mg, but can be moderate at this dose. Remember, this starting dose primarily helps your body adjust to the medication with minimal side effects.

If you're not losing weight on Mounjaro 2.5mg or you think it isn't working, remember that 2.5mg is the starting dose, so you’re unlikely to see the full effects at this stage.

Here are a few other reasons why you might not be losing weight:

• The dose is too low – Clinical studies show that people lose more weight when taking higher doses.
• Time needed – Weight loss varies between people. Some see gradual changes that become more noticeable after dose increases.
• Diet & lifestyle factors – Mounjaro works best when combined with a healthy diet and regular physical activity. Adjusting your food choices and doing more exercise might help.
• Metabolic differences – Factors like insulin resistance, hormonal balance and genetics can all affect weight loss progress.
• Body adjustment phase – Early on, your body is adapting to the medication, which may delay visible weight changes.

If you’re concerned about slow progress, speak to your clinician to discuss increasing your dose, or check in with your coach for advice on how to adjust your lifestyle.

It’s completely normal to still feel hungry while taking Mounjaro 2.5mg. This lower dose allows your body to get used to the medication, but you might benefit from a higher dose.

Why you may still feel hungry:

• Time to adjust: It takes time for the medication’s appetite-suppressing effects to take hold, and some people may need a few weeks to notice a significant difference.
• Individual response: Everyone reacts differently to treatment, and while some feel less hungry early on, others may need a dose adjustment to experience the full benefits.

Next steps: As you continue with treatment, you’ll have the opportunity to increase your dose, which typically provides stronger appetite control.

In the meantime: To maximise results, it's important to engage in lifestyle measures while you’re taking Mounjaro, including:

• Prioritising high-protein & fibre-rich meals to keep you fuller for longer
• Staying hydrated, as thirst can sometimes be mistaken for hunger
• Eating mindfully, focusing on portion sizes and hunger cues
• Incorporating movement & activity to support metabolism and overall well-being

If you’re still hungry after increasing your dose, or if you have any concerns, please reach out – we’re here to support you throughout your journey.

No, Mounjaro 2.5 mg should not be taken twice a week. Taking it more frequently than prescribed could increase the risk of side effects without improving effectiveness.

Mounjaro 2.5mg comes in a 3 mL pre-filled injection pen. Each dose contains 2.5mg of Tirzepatide in 0.6 mL of solution. There is also some excess liquid to allow for the priming fluid.

The Mounjaro 2.5mg pen contains four doses (one dose per week), so it should last you four weeks.

While initially approved for diabetes, Mounjaro is now licensed and widely prescribed for weight management. The 2.5mg dose is used for both conditions as a starting point, with clinical evidence supporting its effectiveness for weight loss in non-diabetic patients.

Yes, the SURMOUNT-1 trial published in the New England Journal of Medicine showed participants lost approximately 4% of body weight during the first month on 2.5mg. Greater losses occurred as doses increased in subsequent months.

After completing four weeks on 2.5mg with manageable side effects, most patients increase to 5mg. Your clinician will assess your tolerance, side effects, and initial results to determine if and when a dose increase is appropriate. If you're experiencing strong effects on the 2.5mg dose, or any side effects, you may be advised to remain on this dose until the side effects settle down.

The difference between 2.5mg and 5mg Mounjaro:

• 2.5mg is the starting dose of Mounjaro. It is taken once a week for at least four weeks before increasing to a higher dose.
• 5mg is the first step-up dose of Mounjaro, offering stronger appetite suppression and metabolic effects. It should also be injected once weekly and must be taken for at least four weeks before increasing again.

No, you cannot go directly from 2.5mg to 7.5mg on Mounjaro.

Mounjaro follows a step-up dosing schedule to help your body adjust and reduce the risk of side effects. The recommended progression is:

• Start with 2.5mg (for at least 4 weeks)
• Increase to 5mg (for at least 4 weeks)
• Increase to 7.5mg, if tolerated and needed

Skipping doses or jumping directly from 2.5mg to 7.5mg could lead to stronger side effects.

Always follow the recommended titration schedule as advised by your clinician.