Mounjaro 2.5mg Injection

You may experience some side effects on Mounjaro 2.5mg, including:

• Nausea (most common, usually mild and temporary)
• Diarrhoea or constipation
• Stomach pain or discomfort
• Loss of appetite
• Indigestion or bloating
• Fatigue
• Mild injection site reactions (redness, itching or swelling)

It's normal to experience some mild, temporary side effects when you start taking Mounjaro or after increasing your dose.

If you need support managing side effects, call our support line on 020 3912 9885 and press 2 to speak to a clinician within minutes (Monday to Friday, 9am - 5pm).

It’s completely normal to still feel hungry while taking Mounjaro 2.5mg. This lower dose allows your body to get used to the medication, but you might benefit from a higher dose.

Why you may still feel hungry:

• Time to adjust: It takes time for the medication’s appetite-suppressing effects to take hold, and some people may need a few weeks to notice a significant difference.
• Individual response: Everyone reacts differently to treatment, and while some feel less hungry early on, others may need a dose adjustment to experience the full benefits.

Next steps: As you continue with treatment, you’ll have the opportunity to increase your dose, which typically provides stronger appetite control.

In the meantime: To maximise results, it's important to engage in lifestyle measures while you’re taking Mounjaro, including:

• Prioritising high-protein & fibre-rich meals to keep you fuller for longer
• Staying hydrated, as thirst can sometimes be mistaken for hunger
• Eating mindfully, focusing on portion sizes and hunger cues
• Incorporating movement & activity to support metabolism and overall well-being

If you’re still hungry after increasing your dose, or if you have any concerns, please reach out – we’re here to support you throughout your journey.

No, Mounjaro 2.5 mg should not be taken twice a week. Taking it more frequently than prescribed could increase the risk of side effects without improving effectiveness.

Inject once a week on the same day each week.

Inject under the skin (subcutaneous fat) in the abdomen, thigh, or upper arm (rotate sites to minimise irritation).

1. Prepare your pen

• Pull off the cap and check the liquid (it should be clear to slightly yellow).
• Wipe the red inner seal with an alcohol swab.
• Attach a new needle (never use a bent/damaged one).

2. Prime the pen (before first use)

• Turn the dose knob until you hear 2 clicks and see a long line in the dose window.
• Hold the pen needle-up, and press the dose knob until 0 appears in the window.
• Look for a tiny drop of liquid at the needle tip. If none appears, repeat up to 3 times or change the needle if needed. If there’s still no liquid, contact Voy.

3. Inject your dose

• Turn the dose knob until 1 appears in the window.
• Insert the needle into your abdomen, thigh, or upper arm.
• Press and hold the button until you see the 0 in the dosage window, and then wait for 5 seconds.

4. After the injection

• Remove the needle carefully, place the outer cap back on and dispose of it in a sharps bin.
• Do not store the pen with the needle attached – always recap the pen.

Find a detailed step-by-step walkthrough, along with a video, in our "How to Inject Mounjaro" guide.

Mounjaro 2.5mg comes in a 3 mL pre-filled injection pen. Each dose contains 2.5mg of Tirzepatide in 0.6 mL of solution. There is also some excess liquid to allow for the priming fluid

The Mounjaro 2.5mg pen contains four doses (one dose per week), so it should last you four weeks.

The difference between 2.5mg and 5mg Mounjaro:

• 2.5mg is the starting dose of Mounjaro. It is taken once a week for at least four weeks before increasing to a higher dose.
• 5mg is the first step-up dose of Mounjaro, offering stronger appetite suppression and metabolic effects. It should also be injected once weekly and must be taken for at least four weeks before increasing again.

No, you cannot go directly from 2.5mg to 7.5mg on Mounjaro.

Mounjaro follows a step-up dosing schedule to help your body adjust and reduce the risk of side effects. The recommended progression is:

• Start with 2.5mg (for at least 4 weeks)
• Increase to 5mg (for at least 4 weeks)
• Increase to 7.5mg, if tolerated and needed

Skipping doses or jumping directly from 2.5mg to 7.5mg could lead to stronger side effects.

Always follow the recommended titration schedule as advised by your clinician.