Mean weight loss for digitally engaged patients, vs 17.6% with medication alone.
Mean weight loss
One of the UK's largest real-world weight management evidence bases: 27 publications and counting, built from 350,000 patients.
Digital support changes what GLP-1 medication can achieve.
Community-led delivery changes who engages, and who succeeds.
Psychological wraparound converts medication response into lasting change.
Those at highest risk are the most likely to engage.
Johnson H, Clift AK, Reisel D, Huang DR. Digital engagement significantly enhances weight loss outcomes in adults with obesity treated with tirzepatide (n=126,553). JMIR preprint, accepted. https://pmc.ncbi.nlm.nih.gov/articles/PMC12856402/
Johnson H, Clift AK, Reisel D, Huang DR. Digital engagement enhances weight loss outcomes with tirzepatide: cohort study of 66,846 adults. Obesity Week 2025 Poster-446. Listed at https://obesityweek.org/wp-content/uploads/2023/04/OW25-Posters-by-Number-as-of-10-30-2025.pdf — internal source: poster_446_OW_Tirz_Johnson_1.pdf
Johnson H, Clift AK, Reisel D, Huang DR. Digital engagement enhances weight loss outcomes in adults treated with GLP-1 receptor agonists. J Med Internet Res 2025; 27: e69466. https://www.jmir.org/2025/1/e69466