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Home/Guides & Tips/Testosterone/

What is testosterone?

TRT

What is testosterone?

Testosterone plays a key role in keeping men feeling physically and mentally at their best. Here’s why this hormone matters.

clinician image

Medically reviewed by Medical Director

Dr. Jeff Foster - Men’s Health & TRT Specialist

iconUpdated 23rd December 2025

Testosterone is the main male sex hormone. It’s primarily made in the testes and plays a key role in keeping you physically and mentally well.

So, what’s the function of testosterone and why does it matter? Here’s what to know.

What does testosterone do?

Testosterone is responsible for the development and function of your male features, from childhood through to puberty and beyond. That includes your reproductive organs growing, your voice deepening, sperm production, libido and erectile function.

But testosterone acts on loads of different systems, too. It regulates your muscle growth, bone density, metabolism and mood, and is linked to cognitive function.

Benefits of testosterone, including improved mood, higher energy, increased sex drive, and erectile function.

Is testosterone a steroid?

Testosterone is a steroid hormone. While the word “steroid” is often linked to performance-enhancing anabolic drugs, testosterone itself is a naturally occurring hormone.

Our guide on testosterone and steroids unpacks how testosterone replacement therapy (TRT) differs from anabolic steroids, and why the two shouldn’t be confused.

How is testosterone measured?

Doctors measure your testosterone levels with a good old-fashioned blood test.

The test is done in the morning before you eat anything. Because testosterone levels can be influenced by different factors, from your diet to stress, you’ll be tested at least twice to confirm you’re actually deficient.

Feeling drained and unfocused?
It might be low testosterone. Get answers fast with an at-home blood test.

Many men also wonder whether habits like masturbation affect their testosterone levels, but research shows it doesn’t.

What are normal levels of testosterone for a man?

Here’s a chart showing average levels of testosterone by age.

Age range
25-34
35-44
45-54
55-64
65-74
75-84
85-100
Av. total testosterone (nmol/l)
21.38
23.14
21.02
19.49
18.15
16.32
13.05
Av. free testosterone (nmol/l)
0.428
0.356
0.314
0.288
0.239
0.207
0.186

The British Society of Sexual Medicine recommends that testosterone replacement therapy (TRT) should be offered to patients with levels below 12nmol/l total testosterone or free testosterone of 0.225nmol/l and below. But you can only usually get TRT on the NHS if your total testosterone levels are less than 8nmol/L (this varies based on your region in the UK).

Low testosterone

Up to 35% of men aged over 45 are estimated to have low T. It’s more common with age: testosterone naturally starts to decline after you turn 30. Not everyone who has low levels of testosterone will have symptoms but majority of men don't know what their baseline is.

Erectile dysfunction, loss of early morning erections and low libido are the three most common. Other include:

  • Reduced energy
  • Depression, anxiety, irritability
  • Reduced strength
  • Reduced enjoyment in life

High testosterone

Having too much testosterone can be a problem, too. It’s not common for men to naturally have abnormally high T, though it can sometimes be caused by underlying medical issues, or use of anabolic steroids. Symptoms include:

  • Acne
  • Prostate enlargement and trouble urinating
  • Risk of clots

It's important to note the goal of testosterone replacement therapy is to normalise low testosterone

Learn more about high testosterone in men—its signs, causes and how to lower it safely.

Types of testosterone

There are two main types of testosterone to be aware of.

Free testosterone

Most testosterone in your blood is attached (or “bound”) to proteins. This T is not active and can’t be put to use in your body. Free tesosterone measures the testosterone that isn't stuck to proteins, that's free to be used by the body.

Total testosterone

This is the overall amount of testosterone in your blood, free and bound. It’s a good first test for low T because it gives a general picture of your hormone levels.

Which forms of testosterone are used for TRT?

Testosterone replacement therapy (TRT) is a synthetic version of T that’s used to treat testosterone deficiency.

But what types of testosterone are used for TRT? Available medicines include:

  • Testosterone undecanoate (tablets or injection, such as Nebido)
  • Testosterone enanthate (injection)
  • Testosterone cypionate (injection)

Each medicine has its pros and cons, and your doctor will advise on what’s best for you. If you’re prescribed injections, understanding how and where to inject testosterone can make the process more comfortable and effective.

Make sure you get TRT from a registered provider (find this information on their website). Otherwise, you can’t guarantee that TRT is safe, authentic or in-date.

Why testosterone matters

Having balanced testosterone keeps you at your best, physically and mentally. And TRT can help get you there.
Take our short quiz and order an at-home, finger-prick blood test to get started. Find out your level.

A stronger, sharper you
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FAQ

What is testosterone: FAQs

Continue reading

  • Male menopause (andropause)
  • Benefits of testosterone replacement therapy
  • Testosterone gel for men
  • Enclomiphene citrate
  • Subcutaneous testosterone injections
  • TRT side effects
  • Once you start testosterone therapy, can you stop?
  • Oestradiol levels in men
  • Does ashwagandha increase testosterone?
  • Does nicotine increase testosterone?
  • TRT cost in the UK
  • Men’s health stigma around low testosterone
DisclaimerAt Voy, we ensure that everything you read in our blog is medically reviewed and approved. However, the information provided is not meant to replace professional medical advice, diagnosis, or treatment. It should not be relied upon for specific medical advice.
References
icon¹

Abouelmagd, Alaa Abdrabou, et al. “Efficacy and Safety of Retatrutide, a Novel GLP-1, GIP, and Glucagon Receptor Agonist for Obesity Treatment: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.” Proceedings (Baylor University. Medical Center)scribble-underline, vol. 38, no. 3, 2025, pp. 291–303. https://pmc.ncbi.nlm.nih.gov/articles/PMC12026077/

icon²

Jastreboff, Ania M., et al. “Body Composition Changes with Retatrutide in Adults with Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial.” The Lancet Diabetes & Endocrinologyscribble-underline, vol. 15, 2025, pp. 112–123. https://www.sciencedirect.com/science/article/abs/pii/S2213858725000920.

icon³

Jastreboff, Ania M., et al. “Triple–Hormone-Receptor Agonist Retatrutide for Obesity.” The New England Journal of Medicinescribble-underline, vol. 389, no. 6, 2023, pp. 514–526. https://pubmed.ncbi.nlm.nih.gov/37366315/

icon⁴

Rosenstock, Julio, et al. “Retatrutide, a GIP, GLP-1 and Glucagon Receptor Agonist, for People with Type 2 Diabetes: A Randomised, Double-Blind, Placebo and Active-Controlled, Parallel-Group, Phase 2 Trial Conducted in the USA.” The Lancetscribble-underline, vol. 402, no. 10401, 2023, pp. 529–544. https://pubmed.ncbi.nlm.nih.gov/37385280/

icon⁵

U.S. National Library of Medicine. “A Study of Retatrutide (LY3437943) in Participants with Obesity or Overweight (TRIUMPH-1) (NCT05929066).” ClinicalTrials.govscribble-underline. https://clinicaltrials.gov/study/NCT05929066. Accessed 3 Nov. 2025.

icon⁶

U.S. National Library of Medicine. “A Study of Retatrutide (LY3437943) in Participants with Obesity (Maintenance of Weight Loss) (NCT06859268).” ClinicalTrials.govscribble-underline. https://clinicaltrials.gov/study/NCT06859268. Accessed 3 Nov. 2025.

icon⁷

Zheng, Z., et al. “Glucagon-Like Peptide-1 Receptor: Mechanisms and Advances in Therapy.” Signal Transduction and Targeted Therapyscribble-underline, 2024. https://www.nature.com/articles/s41392-024-01931-z

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